115 ASSOCIATION BETWEEN ADIPOKINES AND PROGRESSION OF HAND OSTEOARTHRITIS
نویسندگان
چکیده
منابع مشابه
Association between serum levels of Adipokines and Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder associated with metabolic disorders and infertility. Evidence suggests that the adipose tissue secreted products, adipokines, play an important role in the pathophysiology of PCOS. Reciprocally, PCOS influences on the adipokines serum content, also on gene or protein expression of some of them. Finding out of assoc...
متن کاملAssociation between leptin, adiponectin and resistin and long-term progression of hand osteoarthritis.
OBJECTIVE To investigate the association between baseline serum adipokines levels-leptin, adiponectin and resistin-and long-term progression of hand osteoarthritis (HOA). METHODS Baseline and 6-year radiographs of 164 patients (mean age 60 years, 81% women) with HOA (defined as a Kellgren and Lawrence score ≥2 in at least two hand joints) were assessed for joint space narrowing (JSN) in 32 ha...
متن کاملClustering of hand osteoarthritis progression and its relationship to progression of osteoarthritis at the knee.
OBJECTIVE To investigate patterns of osteoarthritis (OA) progression within hand joints and the relationship between hand OA progression and progression of OA at the knee. METHODS Radiographic progression over 6 years, defined as change in osteophytes or joint space narrowing above the smallest detectable change, was assessed on hand and knee radiographs of 236 hand OA patients participating ...
متن کاملAssociation Between Overweight and Obesity and Risk of Clinically Diagnosed Knee, Hip, and Hand Osteoarthritis
Objective. Studies of previous cohorts have demonstrated an association between a status of overweight/ obesity and the presence of knee and hand osteoarthritis (OA). However, no data on the effect of these factors on the OA burden are available. The aim of the present study was to analyze the effect of being overweight or obese on the incidence of routinely diagnosed knee, hip, and hand OA. Me...
متن کاملAdipokines and Osteoarthritis: Novel Molecules Involved in the Pathogenesis and Progression of Disease
Obesity has been considered a risk factor for osteoarthritis and it is usually accepted that obesity contributes to the development and progression of osteoarthritis by increasing mechanical load of the joints. Nevertheless, recent advances in the physiology of white adipose tissue evidenced that fat cells produce a plethora of factors, called adipokines, which have a critical role in the devel...
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ژورنال
عنوان ژورنال: Osteoarthritis and Cartilage
سال: 2010
ISSN: 1063-4584
DOI: 10.1016/s1063-4584(10)60142-2